ANDROLOGY - Invited Review

Vol. 49 No. 2 (2023): Urology Research and Practice

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Published: Oct 26, 2020
Keywords:
Andrology; azoospermia; male infertility

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Tharu Tharakan
Department of Urology, Imperial Healthcare NHS Trust, Charing Cross Hospital, London, UK
Rong Luo
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Daniel Foran
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Miles Smith
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Channa N. Jayasena
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Suks Minhas
Department of Urology, Imperial Healthcare NHS Trust, Charing Cross Hospital, London, UK

Strategies in Infertile Azoospermic Patients with Negative Microdissection Testicular Sperm Extraction Surgery

Main Article Content

Tharu Tharakan
Department of Urology, Imperial Healthcare NHS Trust, Charing Cross Hospital, London, UK
Rong Luo
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Daniel Foran
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Miles Smith
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Channa N. Jayasena
Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK
Suks Minhas
Department of Urology, Imperial Healthcare NHS Trust, Charing Cross Hospital, London, UK

Abstract

Non-obstructive azoospermia is reported to affect 1 in 100 men, and despite advances in surgical practice, the succesful sperm retrieval rate for microdissection testicular sperm extraction surgery (mTESE) is only 46%. This article reviews the potential causes for mTESE failure and provides a management strategy to guide the clinicians on how to treat this challenging cohort of patients.



Cite this article as: Tharakan T, Luo R, Foran D, Smith M, Jayasena CN, Minhas S. Strategies in infertile azoospermic patients with negative microdissection testicular sperm extraction surgery. Urol Res Pract., 2023;49(2):65-72.


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